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Ibogaine is a natural occurring psychoactive plant alkaloid. It is harvested and purified from the root bark of the Tabernanthe Iboga plant. Tabernanthe Iboga plant is found in the jungles the western Africa. Originally, Gabon, people of the central western Africa have discovered this plant. They are using it for medicinal healing as well as for ritualistic ceremonies.

The stimulation effect of Tabernanthe Iboga plant in crude or powdered form is mild, but the potential stimulation and hallucination is reported with its alkaloid or extract.


The therapeutic use of Tabernanthe iboga plant is generally for depression, drug addiction and other mental diseases. Here are some beneficial effects of Iboga tree.

Mental stress and Depression

However, the use of Tabernanthe iboga in mental stress and depression is not common, but it can increase serotonin levels in the brain, which can result in feeling good and getting rid of depression and negative thoughts. However, there are possible chances of developing dependence on Tabernanthe iboga for this purpose, so it should be used with caution and under medical supervision. (1)

Opiate addiction

Tabernanthe iboga in crude form, extract and its alkaloid is used in the treatment of opiate addiction. The de-addiction therapy can continue for a few days to reduce the physical dependence of person on opiate compounds. (2)

Alcohol Addiction

Studies show that Tabernanthe iboga is also effective for interrupting addiction to alcohol. It can suppress habit of alcohol intake. It might have modulating effects on neuronal system, which is involved in drinking behavior. Thus, it can reduce alcohol consumption. (345)

Nicotine addiction

Studies also concluded that Iboga tree and its extract could give relief from nicotine addiction. The alkaloid of Iboga plant has effects on serotonin levels in the brain, which might help reducing urge to take nicotine or other drugs. (67)

Drug Addiction

Some people are using Iboga tree for getting rid of drug addiction. Iboga has anti-addiction effects. These effects have analyzed in many animal studies and reported in human. However, the pharmacological action of its extract or alkaloid is quite complex and might affect different neurotransmitters in the brain. It might have modulating effects, which helps suppressing urge to take drugs. (89)

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